Human health, animal health and food industry

Active Ingredient

Manufacturing for third parties

DR Healthcare manufactures and markets the active substance (Diamine Oxidase – DAO enzyme) for third parties, both for human and animal use.

We make available to pharmaceutical and food companies that are looking for a reliable supplier, the highest levels of quality, regulatory support and production of Diamine Oxidase, manufactured in our enzyme production plant located in Tarragona (Spain).

The production of this ADI (Active Dietary Ingredient) is vertically integrated so it is able to control the intermediates of its manufacturing.


Customized solutions

DR Healthcare stands out as a leading company in the production of Diamino Oxidasa, which allows us to offer tailored solutions for use in the veterinary, animal health and food sectors.

Our solutions based on Diamino Oxidase are adapted to the new food control standards, which stipulate the control of histamine levels in order to avoid risks of poisoning due to the consumption of large amounts of this biogenic amine present in food.



Press releases and media’s news

Medical nutrition industry prepares for the first International Congress on DAO Deficiency – NutraSalud

Article published in NutraSalud magazine on November 2, 2021. Publication link International experts on the various disorders caused by DAO deficiency, in fields as diverse as the digestive system, neurology, genetics, psychiatry, allergology and nutrition, will participate in the first International Congress on DAO Deficiency, organized by DR Healthcare. DR...

Scientific and clinical evidence in DAO deficiency

Intestinal Dysbiosis in Patients with Histamine Intolerance

New study published about microbiota, histamine intolerance and DAO deficiency by the research team of the University of Barcelona (Dr. Mª Carmen Vidal). Adding clinical and scientific evidence every day. Download the scientific paper through here Abstract: An underlying cause of histamine intolerance is diamine oxidase (DAO) deficiency, which leads to defective...


Are underestimated the amounts of biogenic amines in diets low in histamine ?

  Diets low in histamine are currently used to reduce symptoms of intolerance to histamine, a disorder in the homeostasis of this molecule that increases its blood levels, due mainly to the reduction of the activity of the diamine oxidase (DAO) enzyme. In fact, these diets low in histamine exclude foods, many of them of plant origin, that patients associate with the...

Activities and events

Conference “Migraine and other functional symptoms of DAO Deficiency” in the Official College of Pharmaceutits of Tarragona

On November 4 at 15 hours, will speak about the DAO Deficiency. Title: Migraine and other functional symptoms of DAO Deficiency Speakers: Dr. Ramón Tormo Carnicé. Chief Gastroenterology Hospital Quirón Barcelona Adriana Duelo Dietitian, Specialist in DAO Deficiency Location: Col•legi Oficial de Farmacèutics de Tarragona