Human health, animal health and food industry

Active Ingredient

Manufacturing for third parties

DR Healthcare manufactures and markets the active substance (Diamine Oxidase – DAO enzyme) for third parties, both for human and animal use.

We make available to pharmaceutical and food companies that are looking for a reliable supplier, the highest levels of quality, regulatory support and production of Diamine Oxidase, manufactured in our enzyme production plant located in Tarragona (Spain).

The production of this ADI (Active Dietary Ingredient) is vertically integrated so it is able to control the intermediates of its manufacturing.


Customized solutions

DR Healthcare stands out as a leading company in the production of Diamino Oxidasa, which allows us to offer tailored solutions for use in the veterinary, animal health and food sectors.

Our solutions based on Diamino Oxidase are adapted to the new food control standards, which stipulate the control of histamine levels in order to avoid risks of poisoning due to the consumption of large amounts of this biogenic amine present in food.



Press releases and media’s news

AB Mauri set to lead first-ever virtual congress into DAO enzyme deficiency

Article published in bakeryandsnacks.com the 29-oct-2021, by Gill Hyslop. Publication link The business unit of AB Biotek – which is part of the global yeast and bakery ingredients specialist – is hosting the first International Congress of DAO Deficiency online on 4 November....

Scientific and clinical evidence in DAO deficiency

Histamine Intolerance—A Kind of Pseudoallergic Reaction

Biomolecules 2022, 12, 454. https://doi.org/10.3390/biom12030454 Ying Zhao 1,2,† , Xiaoyan Zhang 1,2,† , Hengxi Jin 2 , Lu Chen 1,2, Jiang Ji 1,2,* and Zhongwei Zhang 3,* 1 Department of Dermatology, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China;nanjjzhaoying@126.com (Y.Z.); hiohikari@163.com (X.Z.); chenlu1275@163.com (L.C.)2...


The histamine interposes at Christmas

D Histamine accumulation in the body due to excessive food and alcohol consumption causes gastrointestinal disorders, headaches and migraine. The International Society of DAO Deficiency recommends moderating the intake of food, especially those rich in histamine such as cured meat, smoked products, seafood and typical Christmas dessert, and supplement menu with...

Activities and events

Conference “Migraine and other functional symptoms of DAO deficiency” in INFARMA 2015 on Wednesday 25 March.

Realized by Dr. Ramón Tormo Carnicé, especialist in Gastroenterology and Chief of the Gastroenterology and Nutrition Unit of the Hospital Quirón of Barcelona, and by Adriana Duelo, Dietist-Nutricionist, especialist in DAO deficiency.