What about legumes as a plant source of the DAO enzime?
Ann Nutr Metab 2018;73 (suppl 2): 1-93
Spanish Nutrition Society SEÑ and the Catalan Association of Food Science (ACCA), Barcelona, Spain, june 27-29, 2018
O.Comas-Basté; S.Sánchez-Pérez; R.I. Garza-Guajardo; M.L.Latorre-Moratalla ; M.T.Veciana-Nogués; M.C.Vidal-Carou.
Departament de Nutrició, Ciències de l’Alimentació i Gastonomia. Facultat de Farmàcia i Ciències de l’Alimentació.INSA-UB.XaRTA.Universitat de Barcelona.Santa Coloma de Gramanet.Spain
The use of exogenous diamine oxidase (DAO) enzyme has been recently postulated as a potential strategy for the treatment of histamine intolerance, a disorder in the homeostasis of histamine caused by a reduction of its intestinal degradation. Dietary supplements based on gastro-resistant encapsulated porcine kidney protein extract ara available on the market to reduce the symptoms of this intolerance. Although with scarce scientific research, there are some references about the potential of pea seedlings as a source of DAO.
To study the capacity of legumes and their sprouts to reduce histamine in vitro and evaluate the influence of different growing conditions on this enzymatic activity. If confirmed, legumes could become and advantageous alternative to porcine DAO enzyme from a productive and sustainable perspective.
In vitro DAO activity was measured through and enzymatic assay and the subsequent analysis of remaining histamine by UHPLC-FL. Analysed samples were both raw pulses and prouts of lentils, beans (white, red and black), broad beans, peas, chickpeas and soy.
Effect of dietary fatty acid and micronutrient intake/energy ratio on serum diamine oxidase activity in healthy women
Effect of dietary fatty acid and micronutrient intake/energy ratio on serum diamine oxidase activity in healthy women.
Nutrition. 2017 Jul – Aug;39-40:67-70. doi: 10.1016/j.nut.2017.03.004. Epub 2017 Mar 28.
- Division of Nutrition and Metabolism, Kobe University Graduate School of Health Sciences, Kobe, Japan.
- Department of Therapeutic Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
- Department of Nutrition, Kobe University Hospital, Kobe University School of Medicine, Kobe, Japan.
- Division of Nutrition and Metabolism, Kobe University Graduate School of Health Sciences, Kobe, Japan; Department of Nutrition, Kobe University Hospital, Kobe University School of Medicine, Kobe, Japan. Electronic address: firstname.lastname@example.org.
Serum diamine oxidase (DAO) activity varies to a greater extent in women than in men. DAO activity during the luteal phase was higher than that during the follicular phase in healthy women. Recent reports have indicated that duodenal lipid infusion increased DAO activity in the intestinal lymph in rats. The aim of this study was to elucidate the effect of dietary nutrient intake on serum DAO activity in healthy women.
Thirty-four healthy Japanese women were recruited. Food surveys were performed using dietary records for 3 d during both the follicular and luteal phases. Nutrient intake was calculated and expressed as the energy intake ratio. The correlation between DAO activity and nutrient intake was analyzed.
Serum DAO activity in both phases was positively correlated with intake of long-chain fatty acids, saturated fatty acids, and monounsaturated fatty acids (P < 0.05). Intake of phosphorus, calcium, zinc, magnesium, iron, and vitamin B12 during the luteal phase was positively correlated with serum DAO activity (P < 0.05).
In healthy women, serum DAO activity was influenced by dietary fatty acid and micronutrient intake.
Copyright © 2017 Elsevier Inc. All rights reserved.
Dietary fatty acids; Dietary micronutrients; Long-chain fatty acids; Menstrual cycle; Serum diamine oxidase activity
The diet factor in pediatric and adolescent migraine.Pediatr Neurol. 2003 Jan;28(1):9-15.
- Division of Neurology, Children’s Memorial Hospital, Chicago, Illinois 60614, USA.
Diet can play an important role in the precipitation of headaches in children and adolescents with migraine. The diet factor in pediatric migraine is frequently neglected in favor of preventive drug therapy. The list of foods, beverages, and additives that trigger migraine includes cheese, chocolate, citrus fruits, hot dogs, monosodium glutamate, aspartame, fatty foods, ice cream, caffeine withdrawal, and alcoholic drinks, especially red wine and beer. Underage drinking is a significant potential cause of recurrent headache in today’s adolescent patients. Tyramine, phenylethylamine, histamine, nitrites, and sulfites are involved in the mechanism of food intolerance headache. Immunoglobulin E-mediated food allergy is an infrequent cause. Dietary triggers affect phases of the migraine process by influencing release of serotonin and norepinephrine, causing vasoconstriction or vasodilatation, or by direct stimulation of trigeminal ganglia, brainstem, and cortical neuronal pathways. Treatment begins with a headache and diet diary and the selective avoidance of foods presumed to trigger attacks. A universal migraine diet with simultaneous elimination of all potential food triggers is generally not advised in practice. A well-balanced diet is encouraged, with avoidance of fasting or skipped meals. Long-term prophylactic drug therapy is appropriate only after exclusion of headache-precipitating trigger factors, including dietary factors.