Diagnosis of DAO Deficiency

There are two ways in which the diagnosis can be made: the molecular genetic study of Diamine Oxidase (DAO) activity (AOC1-V) and/or the in vitro diagnostic test measuring DAO enzyme activity in plasma.

Molecular genetic study of Diamine Oxidase (DAO) activity (AOC1-V).

It is a non-invasive test that performs a highly sensitive genotyping of the most relevant genetic variants of the AOC1 gene coding for the DAO enzyme from a saliva sample (buccal mucosa).

Three of these allelic variants of AOC1 are analyzed in this test:

Classification of variants according to the recommendations of the American College of Medical Genetics and Genomics according to nomenclature of HGVS

Classification of variants according to the recommendations of the American College of Medical Genetics and Genomics according to nomenclature of HGVS

Finally, the results report specifies the variants detected in the patient, as well as the phenotypic interpretation of reduced DAO activity based on the results obtained.

Click here for more information on the molecular genetic study of Diamine Oxidase (DAO) activity (AOC1-V).

DAO analysis: in vitro diagnostic test to measure the level of DAO (Diamine Oxidase) enzyme activity in plasma.

The DAO® ANALYTICS is an in vitro diagnostic test to measure the level of DAO (Diamine Oxidase) enzyme activity in plasma.

The results determine a reduced DAO enzyme activity when the values of HDU/ml (Histamine Degraded Units/mililiter of blood) are between 80-40 HDU/ml, or very reduced when they are under 40 HDU/ml.

Click here for more information about DAO® Analysis.

INFORMACIÓN COMPLETA SOBRE DÉFICIT DE DAO

Histamine in food

In addition to foods rich in histamine, high intakes of foods rich in other amines such as putrescine, cadaverine, b-phenylethylamine, tryptamine, serotonin, tyramine and agmatine can also lead

Diagnosis of DAO Deficiency

There are two ways in which the diagnosis can be made: the molecular genetic study of Diamine Oxidase (DAO) activity (AOC1-V) and/or the in vitro diagnostic test measuring

Origin of DAO deficiency

The main reason for enzyme dysfunction has a genetic origin.

This justifies the recent belief that chronic pathologies such as migraine are hereditary, when in fact the hereditary factor

Que es el Déficit de DAO
What is DAO Deficiency?

It is an alteration in the metabolism of food histamine that occurs when the activity of the Diamine Oxidase (DAO) enzyme is reduced. That is, when for certain

Histamine in food

In addition to foods rich in histamine, high intakes of foods rich in other amines such as putrescine, cadaverine, b-phenylethylamine, tryptamine, serotonin, tyramine and agmatine can also lead

Diagnosis of DAO Deficiency

There are two ways in which the diagnosis can be made: the molecular genetic study of Diamine Oxidase (DAO) activity (AOC1-V) and/or the in vitro diagnostic test measuring

Origin of DAO deficiency

The main reason for enzyme dysfunction has a genetic origin.

This justifies the recent belief that chronic pathologies such as migraine are hereditary, when in fact the hereditary factor

Que es el Déficit de DAO
What is DAO Deficiency?

It is an alteration in the metabolism of food histamine that occurs when the activity of the Diamine Oxidase (DAO) enzyme is reduced. That is, when for certain

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