{"id":10682,"date":"2018-07-18T09:16:43","date_gmt":"2018-07-18T09:16:43","guid":{"rendered":"https:\/\/new.dr-healthcare.com\/2018\/07\/18\/histamine-reduced-diet-and-increase-of-serum-diamine-oxidase-correlating-to-diet-compliance-in-histamine-intolerance\/"},"modified":"2023-02-17T17:37:51","modified_gmt":"2023-02-17T17:37:51","slug":"histamine-reduced-diet-and-increase-of-serum-diamine-oxidase-correlating-to-diet-compliance-in-histamine-intolerance","status":"publish","type":"post","link":"https:\/\/dr-healthcare.com\/en\/2018\/07\/18\/histamine-reduced-diet-and-increase-of-serum-diamine-oxidase-correlating-to-diet-compliance-in-histamine-intolerance\/","title":{"rendered":"Histamine-reduced diet and increase of serum diamine oxidase correlating to diet compliance in histamine intolerance"},"content":{"rendered":"

download pdf<\/a><\/h3>\n

Eur J Clin Nutr.<\/a><\/span>\u00a02018 Jul 18. doi: 10.1038\/s41430-018-0260-5. [Epub ahead of print]\n

Lackner S<\/a>1<\/sup>,\u00a0Malcher V<\/a>1<\/sup>,\u00a0Enko D<\/a>2<\/sup>,\u00a0Mangge H<\/a>3<\/sup>,\u00a0Holasek SJ<\/a>1<\/sup>,\u00a0Schnedl WJ<\/a>4<\/sup>.<\/div>\n
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Author information<\/span><\/h3>\n
\n
\n
1<\/dt>\n
Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Heinrichstrasse 31a, A-8010, Graz, Austria.<\/dd>\n
2<\/dt>\n
Institute of Laboratory Medicine, General Hospital Steyr, Sierninger Stra\u00dfe 170, A-4400, Steyr, Austria.<\/dd>\n
3<\/dt>\n
Clinical Institute of Medical and Chemical Laboratory Diagnosis, Medical University of Graz, Auenbruggerplatz 30, A-8036, Graz, Austria.<\/dd>\n
4<\/dt>\n
Practice for General Internal Medicine, Dr. Theodor K\u00f6rnerstrasse 19b, A-8600, Bruck, Austria. w.schnedl@dr-schnedl.at.<\/dd>\n<\/dl>\n<\/div>\n<\/div>\n
\n

<\/h3>\n

Abstract<\/h3>\n
\n

Diagnosis of histamine intolerance (HIT) has been based on low serum diamine oxidase (DAO) values, functional gastrointestinal disorders and improvement of symptoms with a histamine-reduced diet (HRD). In a retrospective analysis of outpatients’ charts we identified 101 patients with HIT. After a median of 13 months, a questionnaire was distributed to the patients so that they could be classified into four diet-compliance groups. Calculated with all 101 patients we found an increase of serum DAO values due to a HRD. In the 63 patients that completed the questionnaire, we found that 50 patients had improvement of symptoms or no continuing symptoms. A significant increase of serum DAO levels was found in the patients with strict and occasional diet compliance. Therefore, we demonstrate that a HRD is not only improving symptoms in HIT, but is causing an increase in serum DAO values that correlates with the degree of diet compliance.<\/p>\n<\/div>\n<\/div>\n

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PMID:<\/dt>\n
30022117<\/dd>\n
DOI:<\/dt>\n
10.1038\/s41430-018-0260-5<\/a><\/dd>\n<\/dl>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Diagnosis of histamine intolerance (HIT) has been based on low serum diamine oxidase (DAO) values, functional gastrointestinal disorders and improvement of symptoms with a histamine-reduced diet (HRD). In a retrospective analysis of outpatients’ charts we identified 101 patients with HIT. 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