DR Healthcare provides bulk galenic solutions, crafted with state-of-the-art enzymatic technology, in both primary and secondary packaging, based on the objectives or needs of our clients:
Enzyme Diamine Oxidase (DAO) is thermolabile and sensitive to acidic pH. Therefore, any galenic formulation containing DAO as an active dietary ingredient requires specific manufacturing with temperature and pH control to achieve maximum DAO activity in the final product and ensure enzymatic stability during storage.
Galenic formulations must be gastro-resistant (not only acid-resistant) to allow the enzyme to retain its activity as it passes through the stomach and to ensure efficient release in the small intestine, where DAO metabolizes ingested histamine.
Gastro-resistant capsules and capsules containing gastro-resistant mini-tablets
Gastro-resistant microcapsules with DAO core (Recommended for integration into food matrices or for the development of functional foods)