Tailor-made solutions

DR Healthcare provides advanced galenic solutions in bulk, with primary packaging and/or secondary packaging, according to the customer’s needs

Tailor-made solutions

DR Healthcare provides bulk galenic solutions, crafted with state-of-the-art enzymatic technology, in both primary and secondary packaging, based on the objectives or needs of our clients:

Enzyme Diamine Oxidase (DAO) is thermolabile and sensitive to acidic pH. Therefore, any galenic formulation containing DAO as an active dietary ingredient requires specific manufacturing with temperature and pH control to achieve maximum DAO activity in the final product and ensure enzymatic stability during storage.

Galenic formulations must be gastro-resistant (not only acid-resistant) to allow the enzyme to retain its activity as it passes through the stomach and to ensure efficient release in the small intestine, where DAO metabolizes ingested histamine.

  • Gastro-resistant tablets

  • Gastro-resistant mini-tablets

  • Gastro-resistant capsules and capsules containing gastro-resistant mini-tablets

  • Gastro-resistant microcapsules with DAO core (Recommended for integration into food matrices or for the development of functional foods)

  • Gastro-resistant minicapsules

RELATED INFO

Histamine in food

Several foods provoke histamine accumulation in the organism, but not all are necessarily rich in this amine. High intakes of foods rich in other amines such as putrescine,

Que es el Déficit de DAO
What is DAO Deficiency?

DAO Deficiency is an alteration in the metabolism of food histamine that occurs when the activity of the Diamine Oxidase (DAO) enzyme is reduced. That is, when for

Histamine in food

Several foods provoke histamine accumulation in the organism, but not all are necessarily rich in this amine. High intakes of foods rich in other amines such as putrescine,

Que es el Déficit de DAO
What is DAO Deficiency?

DAO Deficiency is an alteration in the metabolism of food histamine that occurs when the activity of the Diamine Oxidase (DAO) enzyme is reduced. That is, when for