Leading DAO technology

Our technological processes for the extraction and purification of DAO enzyme provide higher enzyme activity than other competitors.

About ABFI

ABF Ingredients (ABFI) is a division of Associated British Foods plc, which comprises a global community of ingredients companies operating under their own identities.

Innovation and licensing

At DR Healthcare we are open to forming strategic alliances with other companies and research and development institutions that complement our business areas to further strengthen our presence and that of our partners globally.



DAO Deficiency awareness campaign. In it, four siblings discover that the different symptoms they suffer from: migraines, fibromyalgia, digestive disorders, atopic skin and ADHD (in the son of one of them), may have a common genetic origin.
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About DR Healthcare

We are a biomedical company dedicated to the production of Diamine Oxidase (DAO) enzyme. We specialise in the research, development, innovation, manufacture, marketing and licensing of new nutraceutical products, functional foods, active ingredients and various tailor-made solutions for the dietary management of Diamine Oxidase (DAO) Deficiency.

We place great emphasis on research and strongly believe in the “company/university” alliance, developing our activities in two R&D&I centres.

DR Healthcare is a division of AB Biotek Human Nutrition & Health.

International DAO Deficiency Congress

The last edition, held on 17 November 2022, closed with a record attendance and consolidated the knowledge on this metabolic disorder.
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More than 1200 congress participants, including doctors, pharmacists, scientists and academics, as well as professionals from the pharmaceutical and food industries.

More than 1000 congress delegates connected live from 48 countries in Europe, North America, Latin America and Asia.

19 lectures by international experts on DAO Deficiency, from its aetiology, its different clinical manifestations and its dietary treatment to the regulatory framework for the therapeutic use of the innovative enzyme diamine oxidase.

What is DAO Deficiency?

DAO Deficiency corresponds to a reduction in the functional activity of the main digestive enzyme responsible for removing histamine from food.

The enzyme diamine oxidase (DAO) is found mainly in the intestinal mucosa, where it plays a crucial role in the digestion of food.

If histamine metabolism is disturbed and DAO activity is insufficient, there is an imbalance between the amount of histamine ingested and the ability to metabolise it. This makes it difficult to break down and eliminate histamine in the urine.

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DR Healthcare products

Available in a wide network of pharmacies and specialist shops. You can also buy them from a number of online stores and from the official DR Healthcare page on Amazon.

Global Partnerships and Alliances

DR Healthcare, leader in the production of the active ingredient Diamine Oxidase, the enzyme DAO, offers customized solutions for use and application in medical nutrition, and in the pharmaceutical and food industries.

DAO for use in humans

Current international regulations around levels of histamine in food demonstrate the necessity and utility of the application of the enzyme DAO in the food industry and in supplements.

DAO for use in animals

Developing veterinary solutions based on Diamine Oxidase for the dietary management of excess histamine and DAO deficiency in domestic animals, livestock and aquaculture.

Latest news on DAO Deficiency

DR Healthcare’s core value is research, with the aim of providing society with innovative functional foods that contribute to improving the quality of life of people suffering from DAO deficiency and its associated symptoms.