DAO Deficiency awareness campaign
A story of DAO Deficiency, in which four siblings discover how different symptoms that affect them may have a common genetic origin.
International Congress of DAO Deficiency
Access the full content of each of the editions held and information on upcoming editions
Patients area
Resolve all your doubts with the answers from our specialists to the most frequently asked questions related to DAO Deficiency.
DAO Deficiency awareness campaign
A story of DAO Deficiency, in which four siblings discover how different symptoms that affect them may have a common genetic origin.
International Congress of DAO Deficiency
Access the full content of each of the editions held and information on upcoming editions
Patients area
Resolve all your doubts with the answers from our specialists to the most frequently asked questions related to DAO Deficiency.
Diagnosis of histamine intolerance (HIT) has been based on low serum diamine oxidase (DAO) values, functional gastrointestinal disorders and improvement of symptoms with a histamine-reduced diet (HRD). In a retrospective analysis of outpatients’ charts we identified 101 patients with HIT. After a median of 13 months, a questionnaire was distributed to the patients so that they could be classified into four diet-compliance groups.
Twenty-two adult patients were recruited and completed four weeks of histamine-free diet. The USS and UAS scores each showed significant differences before and after the histamine-free diet (p=0.010, p=0.006). There was a significant reduction in plasma histamine level after the histamine free-diet, compared with baseline (p=0.010). However, DAO activity did not change after the histamine-free diet (p=0.165).