Human health, animal health and food industry

Active Ingredient

Manufacturing for third parties

DR Healthcare manufactures and markets the active substance (Diamine Oxidase – DAO enzyme) for third parties, both for human and animal use.

We make available to pharmaceutical and food companies that are looking for a reliable supplier, the highest levels of quality, regulatory support and production of Diamine Oxidase, manufactured in our enzyme production plant located in Tarragona (Spain).

The production of this ADI (Active Dietary Ingredient) is vertically integrated so it is able to control the intermediates of its manufacturing.

Customized solutions

DR Healthcare stands out as a leading company in the production of Diamino Oxidasa, which allows us to offer tailored solutions for use in the veterinary, animal health and food sectors.

Our solutions based on Diamino Oxidase are adapted to the new food control standards, which stipulate the control of histamine levels in order to avoid risks of poisoning due to the consumption of large amounts of this biogenic amine present in food.



Press releases and media’s news

Dosfarma – Do you know the difference between DAOfood and Migrasin?

Publication of the article “Do you know the difference between DAOfood and Migrasin? In the blog about health and wellness tips, novel and natural beauty treatments dosfarma.com. Language: Spanish. This paper informatively discusses the role of food histamine and the enzyme diamino oxidase (DAO) in DAO deficiency and its associated pathologies. It also...

Scientific and clinical evidence in DAO deficiency

Association of Diamine oxidase (DAO) variants with the risk for migraine from North Indian population

Association of Diamine oxidase (DAO) variants with the risk for migraine from North Indian population Dowload pdf Sukhvinder Kaura,⁎, Arif Alib, Yaser Siahbalaeic, Uzair Ahmadc, Fazila Nargisc, A.K. Pandeyd, Balkirat Singhe a UGC-PDF, Gene Expression Lab, Department of Biosciences, Jamia Millia Islamia, New Delhi, India b UGC-BSR-FF, Department of Biosciences,...


Are underestimated the amounts of biogenic amines in diets low in histamine ?

  Diets low in histamine are currently used to reduce symptoms of intolerance to histamine, a disorder in the homeostasis of this molecule that increases its blood levels, due mainly to the reduction of the activity of the diamine oxidase (DAO) enzyme. In fact, these diets low in histamine exclude foods, many of them of plant origin, that patients associate with the...

Activities and events


Next Monday 17 June (2019), will take place from 14.00 to 16.00 hours in the University Rovira i Virgili (Edifici N5 Sustainable Chemistry, Assembly Hall.Marcel.li Sunday, 2-4-6, Sescelades Campus 43007-Tarragona, Spain) the training activity “DAO deficiency and the role of the pharmacist in the diagnosis and treatment” (language: Spanish). This training is organized...